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 Dr. Sahar S. Alghamdi, PhD

Assistant Professor
Assistant Professor of Medicinal Chemistry Track, COP-Female Branch

Birth Date


Work Experience


Doctor of Philosophy in Medicinal Chemistry, The University of Tennessee Health Science Center, Tennessee,USA, 2020
Master of Science in Medicinal Chemistry, The University of Florida, Florida, USA, 2016
Bachelor of Science in Pharmacy, King Saud University, Riyadh, KSA, 2012


Research Focus

-Pharmacological, and biological evaluation of synthetic cannabinoid ligands using multiple functional assays (G-protein and β-arrestins signaling) and radioligand binding affinity studies at human CB1 and CB2 receptors.

-Investigation of the anti-inflammatory properties of multiple cannabinoids in neurodegenerative diseases in-vitro models by evaluating the M1 and M2 microglia phenotypes, pro and anti-inflammatory cytokines production, and multiple signaling pathway upon cannabinoid drug treatment in murine (C8B4) and human (immortalized SV40 cells) microglial cells.

-Assessment of protein-ligand molecular interactions (at CB1 and CB2 receptors) that produced specific (experimental) pharmacological profile using computational techniques (GPCR homology models, protein-ligands molecular dynamic simulations MD, flexible and induced fit molecular docking, QSAR studies) using Schrödinger software (prime, glide, desmond, Pharmacophore modeling, 3D-QSAR).